What if your body had a ‘reset’ button?

Ribbit-ing Innovation in Cellular Regeneration and Repair

By Cara Jay

Dr. Sergei Paylian, Bioquark President, Founder and Chief Scientific Officer

Dr. Sergei Paylian, Bioquark President, Founder and Chief Scientific Officer

The trend of plastic surgery to reverse the effects of aging has increased tremendously in recent years. However, achieving a younger appearance through surgery may one day soon prove unnecessary. Bioquark Inc., a bio-pharmaceutical company currently developing proprietary biological drugs, armed with an amphibian-derived biochemical mixture called BQ-A, aims to make going under the knife a fad of the past.

Amphibians & Aging
Students in elementary school learn that amphibians are capable of regenerating lost tails and other appendages. Dr. Sergei Paylian, Bioquark President, Founder and Chief Scientific Officer, took these clues from nature to the lab and got to work on the “cure” for aging, diseased and degenerating cells. “Some species of amphibians and reptiles sprout the missing parts of the body after amputation. These regenerative mechanisms continue to work successfully in nature nowadays, millions of years later,”  said Dr. Paylian.

After years of studying epimorphosis – essentially nature’s “restart” button as it were – and oocytes, the human biological “restart,” scientists at Bioquark presented their findings and plans for the future in September of 2012 at the Rodman and Renshaw Annual Global Investment Conference in New York City.

shutterstock_8634583“Existence of the reprogramming signaling system in amphibian oocytes of African frog Xenopus Laevis was demonstrated for the first time by Nobel Prize winning professor John Gurdon (UK) as far back as 1968, in which frog oocyte extracts were co-cultured with adult human cells,”  said Dr. Paylian. Bioquark has refined this research and discovered that under a special incubation process, post- activated frog oocytes are able to release a very powerful reprogramming semiochemical signal, allowing the oocytes to trigger other cells to “restart.” And voilà, a previously damaged cell is transformed to a younger, healthier state.

Scientists at Bioquark have successfully discovered how to use these principles and apply them to anti-aging technologies. In laboratory studies using BQ-A, Bioquark has increased the lifespan of mice and fruit flies by twice the standard life expectancy. In addition,  BQ-A has reversed typical signs of aging like wrinkling skin and baldness.

Oocytes– The human biological restart button.

Oocytes – The human biological restart button.

Bioquark studies have also had revolutionary results regarding melanoma skin cancer. After 45 days of injections, mice infected with melanoma made a full recovery.

“We have an aggressive yet very disciplined program. Bioquark is offering a solution that can both address regeneration and repair, be delivered to a patient in a traditional bio-pharmaceutical format, and would be cost effective,” said Ira Pastor, CEO Bioquark Inc.

Bioquark is excited to begin human trials in the near future and is currently continuing to raise funds to fuel their revolutionary research. Ira Pastor foresees cosmetic applications of their technology to be available to the public within the next three years. “Bioquark brings to the table possibilities for not just disease treatment but for disease cure, and we look forward to bringing this therapeutic opportunity to the marketplace to the United States and globally,” he said.

For more information on Bioquark Inc., visit